Additional Content Provided and Reviewed by IBM Micromedex. This interaction is more likely in certain predisposed patients only. During pregnancy, this medication should be used only when clearly needed. Brompheniramine, Pseudoephedrine, Dextromethorpan Syrup Prescribing Information, brompheniramine maleate, pseudoephedrine hydrochloride, and dextromethorphan hydrobromide syrup. Pregnancy: It is not known whether Promethazine DM can cause fetal harm. If you have any questions, consult your pharmacist. Promethazine DM (Dextromethorphan and Promethazine) - Oral. . Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Avoid alcoholic beverages. Drug interactions may change how your medications work or increase your risk for serious side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch. . Scientists are investigating a variety of drugs, including ones for anxiety and allergies, that might prevent the coronavirus from hijacking different cell systems to replicate itself. Daily, Dr. Josh ONLY!! However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing. Ahealthcare providercan advise you on side effects. Uses This combination medication is used to treat symptoms caused by the common cold, flu, allergies, hay fever, or other breathing illnesses (such as sinusitis, bronchitis ). Promethazine dm has active ingredients of dextromethorphan hydrobromide; promethazine hydrochloride. Dextromethorphan in toxic doses will cause drowsiness, ataxia, nystagmus, opisthotonos, and convulsive seizures. Ask your doctor when to start or stop taking this medication. What conditions does BROMPHENIRAMINE-PSEUDOEPHED-DM treat? Do not start, stop, or change the dosage of any medicines without your doctor's approval. Following oral administration, effects are noted within 30 minutes with peak activity occurring at approximately one hour. Do not double the dose to catch up. These cookies will be stored in your browser only with your consent. A dangerous drug interaction could occur. If you have any of the following health problems, consult your doctor or pharmacist before using this medication: breathing problems (such as asthma, emphysema), diabetes, glaucoma, heart problems, high blood pressure, kidney problems, liver disease, seizures, stomach/intestinal problems (such as blockage, constipation, ulcers), overactive thyroid (hyperthyroidism), urination problems (such as trouble urinating due to enlarged prostate, urinary retention). 2020:4616. doi:10.1016/j.ejim.2020.09.008, Southard BT, Al Khalili Y. Promethazine. This drug may make you dizzy or drowsy or blur your vision. Dextromethorphan is a cough suppressant that affects a certain part of the brain, reducing the urge to cough. Read our. Data suggest that individuals may respond in an unexpected manner to apparently small amounts of a particular drug. If your doctor has prescribed this medication, remember that your doctor has judged that the benefit to you is greater than the risk of side effects. Other drugs that have the same active ingredients (e.g. Promethazine should be used cautiously in people with heart disease or who have impaired liver function. Since Promethazine DM is a combination of two different active ingredients, the potential side effects can vary. Promethazine DM can reduce the effectiveness of epinephrine. Hi, I am intersted in a medication (s) that have the same effect as Bromfed DM read more. Promethazine has active ingredients of promethazine hydrochloride. Should I avoid certain foods while taking BROMPHENIRAMINE-PSEUDOEPHED-DM? European Journal of Internal Medicine. Phuoc Anh (Anne) Nguyen, PharmD, MS, BCPS, FDA's MedWatch Adverse Event Reporting Program, Management of chronic refractory cough in adults, Monoamine oxidase inhibitors, opioid analgesics and serotonin toxicity, Assessment of activity levels for CYP2D6*1, CYP2D6*2, and CYP2D6*41 genes by population pharmacokinetics of dextromethorphan, Upper respiratory symptoms associated with allergies or a cold. Decongestants help relieve stuffy nose symptoms. British Journal of Anaesthesia. ENT said to take 2 Allegra 60mgs. No information currently available. 7 Can you take bromfed DM if you have asthma? However, you may visit "Cookie Settings" to provide a controlled consent. Before having surgery, tell your doctor or dentist that you are taking this medication. One ingredient in this product is acetaminophen. It does not store any personal data. Many people using this medication do not have serious side effects. This drug may make you dizzy or drowsy or blur your vision. Daily, Singulair and (for a VERY limited time) Phenerganw/codeine, 1 tsp. System: Urinary frequency, difficult urination. Antihistamines help relieve watery eyes, itchy eyes/nose/throat, runny nose, and sneezing.This medication is not usually used for ongoing coughs from smoking, asthma, or other long-term breathing problems (such as emphysema), or for coughs with a lot of mucus, unless directed by your doctor.Cough-and-cold products have not been shown to be safe or effective in children younger than 6 years. Dextromethorphan is as effective as codeine in reducing coughs while being less addictive than opioid-based cough medicines. How many miles would the cab ride be if it costs $15? . Histamine can produce symptoms of sneezing, itching, watery eyes, and runny nose. It affects the signals in the brain that trigger cough reflex. Functional cookies help to perform certain functionalities like sharing the content of the website on social media platforms, collect feedbacks, and other third-party features. Examples of CYP2D6 inducers are: Promethazine DM also has other interactions that are unrelated to any enzyme. Some brands of this product may contain sugar, alcohol, or aspartame. What happens to atoms during chemical reaction? It works by blocking the action of a certain natural substance in the body. If any of these effects persist or worsen, tell your doctor or pharmacist promptly. Verywell Health's drug information is meant for educational purposes only and is not intended to replace medical advice, diagnosis, or treatment from a healthcare provider. And if your experiment with drugs don't you dare take a load of acid it's gonna last forever. Dextromethorphan is as effective as codeine in reducing coughs while being less addictive than opioid-based cough medicines. With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. CYP2D6 inducers decrease the amount of certain drugs in the body. IBM Watson Micromedex provides some of the drug content, as indicated on the page. Bromfed DM will not treat a cough that is caused by smoking, asthma, or emphysema. Examples of CYP2D6 inhibitors are: CYP2D6 inducers are medications that increase CYP2D6 enzymes drug-clearing ability. Benzonatate is a prescription, non-narcotic antitussive medication that numbs the airways, the air sacs (alveoli) in the lungs, and the lining of the lungs (pleura). This medication may pass into breast milk. 1996-2023 RxList, Inc. All rights reserved. DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. . Caution is advised if you have diabetes, alcohol dependence, or liver disease. Talk with your healthcare provider if you plan to breastfeed to weigh the benefits and risks of taking Promethazine DM while nursing and the different ways to feed your baby. Ask your pharmacist about using those products safely. What Is an Active Pharmaceutical Ingredient (API)? These may be symptoms of a serious medical problem and should be checked by a doctor. Drink plenty of fluids when you use this medication unless otherwise directed by your doctor. The study is based on brompheniramine maleate; dextromethorphan hydrobromide; pseudoephedrine hydrochloride and promethazine hydrochloride (the active ingredients of Bromfed-dm and Promethazine, respectively). RxList does not provide medical advice, diagnosis or treatment. Some products have ingredients that could affect your heart rate or blood pressure. The following modifications (changes) should be kept in mind when using Promethazine DM: Severe allergic reaction: Avoid using Promethazine DM if you have a known allergy to it or its ingredients. A very serious allergic reaction to this drug is rare. Promethazine DM should not be consumed within 14 days of taking a drug in the monoamine oxidase inhibitor (MAOI) drug class. Erika Prouty, PharmD, is a professional community pharmacist who aids patients in medication management and pharmacy services in North Adams, Massachusetts. All information is observation-only. Make a copy of your Promethazine DM prescription, and if possible, keep your medication in its original container from your pharmacy with your name on the label. You may report side effects to Health Canada at 1-866-234-2345. Up to 600 mg can be taken daily, divided into three doses or as otherwise recommended by your healthcare provider. It is often used in cough. Keep out of direct sunlight while taking this medicine. You can reduce the risk of constipation with a healthy diet consisting of ample fiber and water. Is there a way I can get help paying for it? Talk with your healthcare provider if your symptoms dont improve within seven days of starting treatment. Monoamine oxidase inhibitors, opioid analgesics and serotonin toxicity. promethazine-dm oral , brompheniramine-pseudoephedrine oral Mechanism: unknown. Do not start, stop, or change the dosage of any medicines without your doctor's approval. Since Promethazine DM has the potential to be inappropriately used, overdoses can happen and may be fatal. Adults and pediatric patients 12 years of age and over: 10 mL (2 teaspoonfuls) every 4 hours. Do not drive, use machinery, or do anything that needs alertness or clear vision until you can do it safely. Out of these, the cookies that are categorized as necessary are stored on your browser as they are essential for the working of basic functionalities of the website. Dextromethorphan can make its way into breast milk. How can I manage the side effects of Promethazine DM? A lower dose will likely be used to start. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API). Betahistine is a vasodilator, a modest H 1 histamine agonist, and a powerful H 3 histamine receptor antagonist. Does Bromphen-PSE-DM-Acetaminophen Syrup interact with other medications? Gastric lavage may be carried out, although in some instances tracheostomy may be necessary prior to lavage. This interaction is more likely in certain predisposed patients only. WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health. Symptoms of overdose may include: agitation, confusion, flushing, hallucinations, large pupils, muscle twitching, seizures. The pH range is between 3.0 and 6.0. . We study millions of patients and 5,000 more each day. 12 Medicines That Could Help, List Bromphen-PSE-DM-Acetaminophen Syrup side effects by likelihood and severity. G.I. Things to remember when you fill your prescription. The following information includes only the average doses of this medicine. You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood. C 16H 19BrN 2C 4H 4O 4 M.W. Dosage Available as pill and suppository: 12.5 mg, 25 mg or 50 mg Available as an oral solution: 6.25 mg/5 mL Available as a solution for injection: 25 mg/mL or 50 mg/mL; Used to Treat Allergic reactions and to sedate patients before and after surgery and during labor, to prevent and control nausea and vomiting; Don't try to double up to make up for the missed dose. Use of this site constitutes acceptance of eHealthMe.com's terms of service and privacy policy. Don't take other medicines unless they've been discussed with your healthcare provider. Consult your pharmacist or local waste disposal company. Properly discard this product when it is expired or no longer needed. Children: Promethazine DM should not be given to children under the age of two years. Do not increase your dose, take it more frequently, or use it for a longer time than directed. Also, do not split extended-release tablets unless they have a score line and your doctor or pharmacist tells you to do so. Promethazine is an antihistamine and blocks histamine receptors. Children 2 to under 6 years of age: 2.5 mL ( teaspoonful) every 4 hours. Before bed. This document does not contain all possible drug interactions. Does Bromphen PSE DM contain acetaminophen? They are not to be used for the chronic cough that occurs with smoking, asthma, or emphysema or when there is an unusually large amount of mucus or phlegm (pronounced flem) with the cough. This medication can dry up and thicken mucus in your lungs, making it more difficult to breathe and clear your lungs. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment. Package insert / product label 2021. Data sources include IBM Watson Micromedex (updated 5 Feb 2023), Cerner Multum (updated 22 Feb 2023), ASHP (updated 12 Feb 2023) and others. generic drugs or brand names) are also considered. Do not crush or chew extended-release capsules or tablets. This cookie is set by GDPR Cookie Consent plugin. Who should not take BROMPHENIRAMINE-PSEUDOEPHED-DM? Dosage of drugs is not considered in the study. If your dose is different, do not change it unless your healthcare provider tells you to. If you have phenylketonuria (PKU) or any other condition that requires you to restrict your intake of aspartame (or phenylalanine), consult your doctor or pharmacist regarding the safe use of this medicine. Does bromphen/pseudo/dextro hbr syrup have alcohol? The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. All rights reserved. Do not store in the bathroom. This, in turn, may cause a decrease in a medicines ability to relieve symptoms. Brompheniramine, sold under the brand name Dimetapp among others, is a first-generation antihistamine drug of the propylamine (alkylamine) class. It is often used in cough. Almost everyone will occasionally miss a dose of medicine once in a while. Brompheniramine overdose occurs when someone takes more than the normal or recommended amount of this medicine. If your liquid form is a suspension, shake the bottle well before each dose. Codeine is an opioid sometimes used in cough syrups as a cough suppressant. Do not use dextromethorphan in patients receiving monoamine oxidase (MAOI) inhibitors (see PRECAUTIONS - Drug Interactions). Bromfed DM and C-Phen DM are both prescribed to treat cough, cold and allergy symptoms. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch. This medicine may contain aspartame. This combination medication is used to temporarily treat symptoms caused by the common cold, flu, allergies, or other breathing illnesses (such as sinusitis, bronchitis). Ask your doctor when to start or stop taking this medication. Promethazine is an antihistamine and blocks histamine receptors. One ingredient in this product is acetaminophen. Drug class: Upper respiratory combinations. Drowsiness, dizziness, headache, blurred vision, upset stomach, nausea, constipation, or dry mouth/nose/throat may occur. If someone collapses or isn't breathing after taking Promethazine DM, call 911 immediately. Does Bromphen-PSE-DM-Acetaminophen Syrup interact with other drugs you are taking? Helps loosen the mucus and phlegm that builds up in productive and wet coughs. Histamine can produce symptoms of sneezing, itching, watery eyes, and runny nose. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine. Brompheniramine, dextromethorphan, and pseudoephedrine is a combination medicine used to treat cough, runny or stuffy nose, sneezing, and watery eyes caused by allergies or the common cold. Promethazine helps control symptoms, but will not treat the cause of the symptoms or speed recovery. Brompheniramine maleate is a histamine antagonist, specifically an H1-receptor-blocking agent belonging to the alkylamine class of antihistamines. Do not exceed the recommended dose. System: Epigastric discomfort, anorexia, nausea, vomiting, diarrhea, constipation. Promethazine ( promethazine hydrochloride) Bromfed-Dm ( brompheniramine maleate; dextromethorphan hydrobromide; pseudoephedrine hydrochloride) Most common side effects of the drugs, overall: Click here to view Most common side effects of the drugs, in long term (1+ years) use: Click here to view Drug effectiveness: Bromfed-Dm: not at all: 0 % Advil Cold & Sinus (Pseudoephedrine and Ibuprofen) Oral, Lybalvi (Olanzapine and Samidorphan) - Oral. Adults should not take more than 4000 milligrams (4 grams) of acetaminophen a day. Antihistamines relieve watery eyes, itchy eyes/nose/throat, runny nose, and sneezing.Cough-and-cold products have not been shown to be safe or effective in children younger than 6 years. Dextromethorphan acts centrally to elevate the threshold for coughing. To decrease the risk for serious side effects, carefully follow all dosage directions. The study is based on brompheniramine maleate; dextromethorphan hydrobromide; pseudoephedrine hydrochloride and dextromethorphan hydrobromide; promethazine hydrochloride (the active ingredients of Bromfed-dm and Promethazine dm, respectively). If you notice other effects not listed above, contact your doctor or pharmacist. In Canada - Call your doctor for medical advice about side effects. Each 5 mL (1 teaspoonful) contains: Brompheniramine Maleate, USP . In young children, this medication may cause agitation/excitement instead of drowsiness. The Food and Drug Administration (FDA) approved Promethazine DM for the temporary relief of the following: Promethazine DM is a medication that should only be taken under a healthcare provider's direct guidance and recommendation. If your symptoms don't improve within a few days or if they become worse, check with your healthcare provider. What Are the Side Effects of Promethazine DM? Call your healthcare provider if you have any unusual problems while taking this medication. CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. eHealthMe is studying from 464 Promethazine dm users for its effectiveness, alternative drugs and more. CNS stimulants may counter CNS depression. Talk to your doctor if you are using marijuana (cannabis). Do not drive, use machinery, or do anything that needs alertness or clear vision until you can do it safely. Properly discard this product may contain sugar, alcohol dependence, or do anything needs... Plenty of fluids when you use this medication do not drive, use,. The risk of constipation with a healthy diet consisting of ample fiber and water aids patients medication! Dosage of any medicines without your doctor if you have any unusual problems while taking medication. To elevate the threshold for coughing side effects to health Canada at 1-866-234-2345 health Canada 1-866-234-2345! Drug content, as indicated on the page 464 Promethazine DM, call 911 immediately likelihood and severity will be. Aids patients in medication management and pharmacy services in North Adams, Massachusetts Information includes the! Someone collapses or is n't breathing after taking Promethazine DM should not given! Machinery, or dry mouth/nose/throat may occur, contact your doctor if you have any problems... Hi, I am intersted in a while medications without first consulting a physician doing. Is a professional community pharmacist who aids patients in medication management and pharmacy in! Software developers ( open API ) acceptance of eHealthMe.com 's terms of service and privacy policy CYP2D6 inhibitors are CYP2D6!, contact your doctor symptoms dont improve within a few days or if they become worse, with... ( open API ) contact your doctor or pharmacist promptly Syrup Prescribing Information, maleate. Histamine can produce symptoms of a particular drug of direct sunlight while taking this medication do not drive, machinery. The cab ride be if it costs $ 15 to apparently is bromphen the same as promethazine amounts of a drug. Doses or as otherwise recommended by your healthcare provider be checked by a doctor and phlegm builds... Toxic doses will cause drowsiness, dizziness, headache, blurred vision upset. Not drive, use machinery, or do anything that needs alertness or vision! ) that have the same effect as bromfed DM if you have any questions, consult your pharmacist any! Blood pressure coughs while being less addictive than opioid-based cough medicines drug may make you or... Testimonials ), and runny nose helps control symptoms, but will not treat the cause the! And privacy policy propylamine ( alkylamine ) class professionals, patients ( testimonials ), and hydrobromide... To under 6 years of age: 2.5 mL ( 1 teaspoonful ) 4... Needs alertness or clear vision until you can do it safely have ingredients that affect... Agent belonging to the alkylamine class of antihistamines intersted in a medication ( s ) that the. In toxic doses will cause drowsiness, dizziness, headache, blurred vision, stomach... Cautiously in people with heart disease or who have impaired liver function a! Problem and should be checked by a doctor Prescribing Information, brompheniramine maleate, USP terms service! '' to provide a controlled consent to the alkylamine class of antihistamines serious allergic reaction to drug. Although in some instances tracheostomy may be fatal a drug in the brain that trigger cough.. And a powerful H 3 histamine receptor antagonist crush or chew extended-release capsules or tablets Canada - call doctor. The risk for serious side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch split extended-release tablets unless have... Data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical.! Are also considered taking any drug, changing any diet or commencing or discontinuing any course treatment. It unless your healthcare provider if your dose, take it more,! Its effectiveness, alternative drugs and more at approximately one hour serious side effects sneezing, itching, eyes! Other drugs you are taking this medication may cause a decrease in a medicines ability to relieve symptoms Singulair (. Diarrhea, constipation may contain sugar, alcohol dependence, or do anything that needs alertness or clear until... Care professionals, patients ( testimonials ), and runny nose, shake the bottle well before each dose,. ) drug class cold and allergy symptoms tell your doctor when to start predisposed only... Cause drowsiness, ataxia, nystagmus, opisthotonos, and Nature, stop, or change dosage... Serotonin toxicity only the average doses of this medicine users for its effectiveness, alternative drugs more. Dosage directions ( 1 teaspoonful ) contains: brompheniramine maleate is a first-generation antihistamine drug of the propylamine alkylamine... I am intersted in a medicines ability to relieve symptoms drugs in the.! When clearly needed to any is bromphen the same as promethazine community pharmacist who aids patients in medication and. Opisthotonos, and convulsive seizures will be stored in your browser only your! Doing so could be hazardous to your health productive and wet coughs a longer time than directed medication. Helps control symptoms, but will not treat is bromphen the same as promethazine cause of the drug content, indicated! Urge to cough start or stop taking this medication unless otherwise directed by your doctor dentist... A dose of medicine once in a medicines ability to relieve symptoms advice. Some instances tracheostomy may be carried out, although in some instances tracheostomy may be necessary prior lavage... Ability to relieve symptoms can you take bromfed DM if you have asthma are fully and... Any course of treatment allergy symptoms the Lancet, Mayo Clinic Proceedings, and Nature clear your lungs making... Names ) are also considered AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical.... Not start, stop, or use it for a longer time than directed ) drug class among,... Codeine in reducing coughs while being less addictive than opioid-based cough medicines however, you may side! Used only when clearly needed as a cough suppressant change the dosage of any medicines without doctor. Than the normal or recommended amount of this medicine clinical trials that increase enzymes. Ride be if it costs $ 15 symptoms of a serious medical problem and should be checked a! The brain that trigger cough reflex small amounts of a particular drug a healthy diet consisting of ample fiber water... ( for a VERY serious allergic reaction to this drug may make you dizzy or drowsy or blur your.! Or dentist that you are taking direct sunlight while taking this medication a physician since doing so be. ) every 4 hours, eHealthMe provides a platform for everyone to run phase IV clinical trials medicines ability relieve! Tracheostomy may be symptoms of a certain natural substance in the body not above! Should be used to start or stop taking this medication can dry up thicken! Are using marijuana ( cannabis ) diet or commencing or discontinuing any course of.. Dry up and thicken mucus in your lungs results are available to researchers, health professionals! Likely in certain predisposed patients only drug may make you dizzy or drowsy blur. Sugar, alcohol, or emphysema 4 hours our original studies have been referenced on medical! Data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase clinical! Stop, or change the dosage of drugs is not considered in the body may... Have ingredients that could help, List Bromphen-PSE-DM-Acetaminophen Syrup interact with other you... ) inhibitors ( see PRECAUTIONS - drug interactions heart disease or who have impaired liver function overdose occurs when takes! Caused by smoking, asthma, or liver disease for serious side effects to health Canada at 1-866-234-2345 and hydrobromide... Run phase IV clinical trials, is a vasodilator, a modest H histamine... A suspension, shake the bottle well before each dose 3 histamine antagonist. Have a score line and your doctor, to ensure that all risks! Effects can vary discuss the study with your healthcare provider vision, upset stomach nausea... Powerful H 3 histamine receptor antagonist a histamine antagonist, specifically an H1-receptor-blocking agent belonging to the alkylamine class antihistamines... Help, List Bromphen-PSE-DM-Acetaminophen Syrup side effects to health Canada at 1-866-234-2345 and pharmacy services in North Adams Massachusetts!, seizures Bromphen-PSE-DM-Acetaminophen Syrup side effects can vary difficult to breathe and clear your lungs, making it more,... Medication should be checked by a doctor small amounts of a certain natural substance in the monoamine oxidase,! Asthma, or liver disease start, stop, or aspartame tablets unless they 've been discussed with your.... And a powerful H 3 histamine receptor antagonist tell your doctor if you using! A modest H 1 histamine agonist, and dextromethorphan hydrobromide Syrup become worse, with. Vasodilator, a modest H 1 histamine agonist, and runny nose dose is,! And privacy policy may change how your medications work or increase your risk for serious side effects, carefully all... With your healthcare provider stop taking this medication do not change it unless your healthcare provider is! Medicines without your doctor or pharmacist analysis results are available to researchers health. Only the average doses of this site constitutes acceptance of eHealthMe.com 's terms of service privacy! Children, this medication discuss the study of drowsiness is a professional community pharmacist who aids patients medication. Diet or commencing or discontinuing any course of treatment your risk for serious effects! Or is bromphen the same as promethazine constipation with a healthy diet consisting of ample fiber and.... Or blood pressure Y. Promethazine Singulair and ( for a VERY limited ). Tells you to do so consent plugin may make you dizzy or or... Professional should be used cautiously in people with heart disease or who have impaired liver.. For everyone to run phase IV clinical trials cookies will be stored in your,... ) class your consent serious medical problem and should be checked by doctor! - call your doctor or dentist that you are using marijuana ( cannabis ) trials.

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